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TranHung
09:01 21/03/2026

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_052015.1 RefSeqGene

    Range 5003..156983 Download GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001112.4 → NP_001103.1 double-stranded RNA-specific editase 1 isoform 1

    See identical proteins and their annotated locations for NP_001103.1

    Status: REVIEWED

    Description Transcript Variant: This variant (1), also known as ADAR2a-L1 or DRADA2a, lacks the ALU cassette insert and contains the long C-terminal region, as compared to variant 2. The resulting isoform (1), also known as hRED1-Short, lacks an internal segment, compared to isoform 2. Source sequence(s) AB194370, BC030663, BU726292 Consensus CDS CCDS33590.1 UniProtKB/TrEMBL Q86XN4 Related ENSP00000015877.6, ENST00000348831.9 Conserved Domains (2) summary smart00552Location:322 → 698 ADEAMc; tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase) cd00048Location:79 → 142 DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

  2. NM_001160230.2 → NP_001153702.1 double-stranded RNA-specific editase 1 isoform 7

    See identical proteins and their annotated locations for NP_001153702.1

    Status: REVIEWED

    Description Transcript Variant: This variant (7), also known as ADAR2d, lacks the ALU cassette insert and an alternate segment in the 3' coding region, compared to variant 2. The resulting isoform (7) lacks an internal segment and has a shorter and distinct C-terminus, compared to isoform 2, and contains the short C-terminal region. Variants 7 and 10 encode the same isoform. Source sequence(s) AB194373, BC030663, BU726292 UniProtKB/TrEMBL Q86XN4 Conserved Domains (2) summary smart00552Location:322 → 672 ADEAMc; tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase) cd00048Location:79 → 142 DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

  3. NM_001346687.2 → NP_001333616.1 double-stranded RNA-specific editase 1 isoform 8

    Status: REVIEWED

    Source sequence(s) AL133499, BU726292, BX322560, FJ169506 Consensus CDS CCDS93105.1 UniProtKB/TrEMBL A0A994J4V7, O43263 Related ENSP00000516123.1, ENST00000705393.1

  4. NM_001346688.2 → NP_001333617.1 double-stranded RNA-specific editase 1 isoform 7

    Status: REVIEWED

    Description Transcript Variant: Variants 7 and 10 encode the same isoform (7). Source sequence(s) AL133499, AP001579, BU726292, BX322560 UniProtKB/TrEMBL Q86XN4

  5. NM_001410722.1 → NP_001397651.1 double-stranded RNA-specific editase 1 isoform 9

    Status: REVIEWED

    Source sequence(s) AL133499, BX322560 Consensus CDS CCDS93106.1 UniProtKB/TrEMBL A0A994J7T5, Q86XN4 Related ENSP00000516122.1, ENST00000705392.1

  6. NM_015833.4 → NP_056648.1 double-stranded RNA-specific editase 1 isoform 2

    See identical proteins and their annotated locations for NP_056648.1

    Status: REVIEWED

    Description Transcript Variant: This variant (2), also known as DRADA2b, represents the longest transcript, which includes the ALU cassette insert and the long C-terminal region. It encodes the longest isoform (2), also known as hRED1-Long. Source sequence(s) AB194370, BC030663, BU726292, U76421 Consensus CDS CCDS33589.1 UniProtKB/Swiss-Prot A6NFK8, A6NJ84, C3TTQ1, C3TTQ2, C9JUP4, G5E9B4, O00395, O00465, O00691, O00692, P78555, P78563, Q4AE77, Q4AE79, Q6P0M9, Q8NFA1, Q8NFD1 UniProtKB/TrEMBL O43263 Related ENSP00000353920.3, ENST00000360697.4 Conserved Domains (3) summary smart00552Location:322 → 738 ADEAMc; tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase) cd19895Location:75 → 146 DSRM_RED1_rpt1; first double-stranded RNA binding motif of RNA-editing deaminase 1 (RED1) and similar proteins cd19898Location:232 → 301 DSRM_RED1_rpt2; second double-stranded RNA binding motif of RNA-editing deaminase 1 (RED1) and similar proteins

  7. NM_015834.4 → NP_056649.1 double-stranded RNA-specific editase 1 isoform 3

    See identical proteins and their annotated locations for NP_056649.1

    Status: REVIEWED

    Description Transcript Variant: This variant (3), also known as DRADA2c, lacks an alternate segment in the 3' coding region, compared to variant 2. The resulting isoform (3) has a shorter and distinct C-terminus, compared to isoform 2, and contains the ALU cassette insert and the short C-terminal region. Source sequence(s) BC030663, BU726292, U76422 Consensus CDS CCDS42970.1 UniProtKB/TrEMBL O43263 Related ENSP00000374513.4, ENST00000389863.8 Conserved Domains (3) summary smart00552Location:322 → 712 ADEAMc; tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase) cd00048Location:79 → 142 DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ... pfam13900Location:471 → 496 GVQW; Putative domain of unknown function

RNA

  1. NR_027672.2 RNA Sequence

    Status: REVIEWED

    Description Transcript Variant: This variant (5), also known as ADAR2g, lacks the second coding exon, the ALU cassette insert, and a segment of the 3' UTR, compared to transcript variant 2. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD), and no protein is expressed by in vitro translation according to Kawahara et al. (PMID: 16297572). Source sequence(s) AB194369, BC030663, BU726292

  2. NR_027673.1 RNA Sequence

    Status: REVIEWED

    Description Transcript Variant: This variant (4) contains an additional 5' exon, lacks the ALU cassette, and lacks a segment of the 3' UTR, compared to variant 2. This variant is represented as non-coding because it contains an uORF that is predicted to inhibit translation of the primary ORF. The transcript is also a candidate for nonsense-mediated mRNA decay (NMD). Source sequence(s) AB194370, AY135659, BC030663, BU726292

  3. NR_027674.2 RNA Sequence

    Status: REVIEWED

    Description Transcript Variant: This variant (6), also known as ADAR2a-L2, lacks the ALU cassette insert and a segment of the 3' UTR, compared to variant 2. This variant is represented as non-coding because the additional splicing in the 3' UTR renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). Source sequence(s) AB194371, BC030663, BU726292

  4. NR_073200.2 RNA Sequence

    Status: REVIEWED

    Description Transcript Variant: This variant (8) lacks an internal portion of the last exon compared to variant 2. This variant is represented as non-coding because the additional splicing in the 3' UTR renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). Source sequence(s) BC030663, BU726292, U76421

  5. NR_144483.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s) AB194372, BC030663, BU726292